Dynamic changes in histone deacetylases following kidney ischemia-reperfusion injury are critical for promoting proximal tubule proliferation

Deranged histone deacetylase (HDAC) activity causes uncontrolled proliferation, inflammation, fibrosis, and organ damage. It is unclear whether deranged HDAC activity results in acute kidney injury in the renal hypoperfusion model of bilateral ischemia-reperfusion injury (IRI) and whether in vivo in...

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Bibliografiske detaljer
Udgivet i:Am J Physiol Renal Physiol
Main Authors: Hyndman, Kelly A., Kasztan, Malgorzata, Mendoza, Luciano D., Monteiro-Pai, Sureena
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6580243/
https://ncbi.nlm.nih.gov/pubmed/30810062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00499.2018
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