Proximal Tubule CD73 Is Critical in Renal Ischemia-Reperfusion Injury Protection

CD73-derived adenosine plays an anti-inflammatory role in various organs. However, its role in renal ischemia-reperfusion injury (IRI) is controversial. We targeted CD73 mutant mice to determine the function of CD73 expressed by various renal cell types under mild IRI conditions. Mice with CD73 dele...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Am Soc Nephrol
Egile Nagusiak: Sung, Sun-sang J., Li, Li, Huang, Liping, Lawler, Jessica, Ye, Hong, Rosin, Diane L., Vincent, Issah S., Le, Thu H., Yu, Jing, Görldt, Nicole, Schrader, Jürgen, Okusa, Mark D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Nephrology 2017
Gaiak:
Basic Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328157/
https://ncbi.nlm.nih.gov/pubmed/27628903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2016020229
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