Proximal Tubule CD73 Is Critical in Renal Ischemia-Reperfusion Injury Protection

CD73-derived adenosine plays an anti-inflammatory role in various organs. However, its role in renal ischemia-reperfusion injury (IRI) is controversial. We targeted CD73 mutant mice to determine the function of CD73 expressed by various renal cell types under mild IRI conditions. Mice with CD73 dele...

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Detalles Bibliográficos
Publicado en:J Am Soc Nephrol
Autores principales: Sung, Sun-sang J., Li, Li, Huang, Liping, Lawler, Jessica, Ye, Hong, Rosin, Diane L., Vincent, Issah S., Le, Thu H., Yu, Jing, Görldt, Nicole, Schrader, Jürgen, Okusa, Mark D.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Nephrology 2017
Materias:
Basic Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328157/
https://ncbi.nlm.nih.gov/pubmed/27628903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2016020229
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