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Perivascular CD73(+) cells attenuate inflammation and interstitial fibrosis in the kidney microenvironment
Progressive tubulointerstitial fibrosis may occur after acute kidney injury due to persistent inflammation. Purinergic signaling by 5′-ectonucleotidase, CD73, an enzyme that converts AMP to adenosine on the extracellular surface, can suppress inflammation. The role of CD73 in progressive kidney fibr...
Enregistré dans:
| Publié dans: | Am J Physiol Renal Physiol |
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| Auteurs principaux: | , , , , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Physiological Society
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6766625/ https://ncbi.nlm.nih.gov/pubmed/31364375 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00243.2019 |
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