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Dynamic changes in histone deacetylases following kidney ischemia-reperfusion injury are critical for promoting proximal tubule proliferation

Deranged histone deacetylase (HDAC) activity causes uncontrolled proliferation, inflammation, fibrosis, and organ damage. It is unclear whether deranged HDAC activity results in acute kidney injury in the renal hypoperfusion model of bilateral ischemia-reperfusion injury (IRI) and whether in vivo in...

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Detalhes bibliográficos
Publicado no:Am J Physiol Renal Physiol
Main Authors: Hyndman, Kelly A., Kasztan, Malgorzata, Mendoza, Luciano D., Monteiro-Pai, Sureena
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6580243/
https://ncbi.nlm.nih.gov/pubmed/30810062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00499.2018
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