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Targeted Deletion of Dicer from Proximal Tubules Protects against Renal Ischemia-Reperfusion Injury

MicroRNAs are endogenous, noncoding, small RNAs that regulate expression and function of genes, but little is known about regulation of microRNA in the kidneys under normal or pathologic states. Here, we generated a mouse model in which the proximal tubular cells lack Dicer, a key enzyme for microRN...

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Bibliografiske detaljer
Main Authors: Wei, Qingqing, Bhatt, Kirti, He, Hong-Zhi, Mi, Qing-Sheng, Haase, Volker H., Dong, Zheng
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Nephrology 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2865746/
https://ncbi.nlm.nih.gov/pubmed/20360310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2009070718
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