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Targeted Deletion of Dicer from Proximal Tubules Protects against Renal Ischemia-Reperfusion Injury

MicroRNAs are endogenous, noncoding, small RNAs that regulate expression and function of genes, but little is known about regulation of microRNA in the kidneys under normal or pathologic states. Here, we generated a mouse model in which the proximal tubular cells lack Dicer, a key enzyme for microRN...

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Main Authors: Wei, Qingqing, Bhatt, Kirti, He, Hong-Zhi, Mi, Qing-Sheng, Haase, Volker H., Dong, Zheng
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society of Nephrology 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2865746/
https://ncbi.nlm.nih.gov/pubmed/20360310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2009070718
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