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Epac1 inhibits PKR to reduce NLRP3 inflammasome proteins in retinal endothelial cells

Purpose: Inflammation has been strongly associated with retinal damage in diseases such as diabetic retinopathy. Several studies have reported that high glucose exposure induces damage to the retinal vasculature. We and others have shown that high glucose can activate the NOD-like receptor family, p...

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Détails bibliographiques
Publié dans:J Inflamm Res
Auteurs principaux: Jiang, Youde, Steinle, Jena J
Format: Artigo
Langue:Inglês
Publié: Dove 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6580119/
https://ncbi.nlm.nih.gov/pubmed/31354329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JIR.S210441
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