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Epac1 inhibits PKR to reduce NLRP3 inflammasome proteins in retinal endothelial cells

Purpose: Inflammation has been strongly associated with retinal damage in diseases such as diabetic retinopathy. Several studies have reported that high glucose exposure induces damage to the retinal vasculature. We and others have shown that high glucose can activate the NOD-like receptor family, p...

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Detalhes bibliográficos
Publicado no:J Inflamm Res
Main Authors: Jiang, Youde, Steinle, Jena J
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6580119/
https://ncbi.nlm.nih.gov/pubmed/31354329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JIR.S210441
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