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Epac1 agonist decreased inflammatory proteins in retinal endothelial cells, and loss of Epac1 increased inflammatory proteins in the retinal vasculature of mice

PURPOSE: Increased inflammatory mediator levels are reported in diabetic retinopathy. We previously reported that β-adrenergic receptor agonists reduced inflammatory mediators in the diabetic retina; however, these agents cannot be given systemically. Here, we investigated whether Epac1 is key to th...

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Detalhes bibliográficos
Publicado no:Mol Vis
Main Authors: Liu, Li, Jiang, Youde, Chahine, Adam, Curtiss, Elizabeth, Steinle, Jena J.
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Vision 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5287445/
https://ncbi.nlm.nih.gov/pubmed/28210097
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