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Epac1 Requires AMPK Phosphorylation to Regulate HMGB1 in the Retinal Vasculature
PURPOSE: To investigate whether AMP-activated protein kinase (AMPK) is required for the reduction of high mobility group box 1 (HMGB1) by exchange proteins activated by cAMP 1 (Epac1) in the retinal vasculature. METHODS: We measured AMPK phosphorylation in normal and diabetic Epac1 floxed and cdh5/E...
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| Publicado no: | Invest Ophthalmol Vis Sci |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Association for Research in Vision and Ophthalmology
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7500149/ https://ncbi.nlm.nih.gov/pubmed/32940662 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.61.11.33 |
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