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Compound 49b Regulates ZO-1 and Occludin Levels in Human Retinal Endothelial Cells and in Mouse Retinal Vasculature
PURPOSE: To investigate whether Epac1 is key to Compound 49b's regulation of zonula occluden 1 (ZO-1) and occludin levels in human retinal endothelial cells (REC) and in an Epac1 vascular-specific conditional knockout mouse retina. METHODS: Primary REC were grown in normal (5 mM) or high glucos...
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| 出版年: | Invest Ophthalmol Vis Sci |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Association for Research in Vision and Ophthalmology
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5256679/ https://ncbi.nlm.nih.gov/pubmed/28114578 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.16-20412 |
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