Determining cellular CTCF and cohesin abundances to constrain 3D genome models

Achieving a quantitative and predictive understanding of 3D genome architecture remains a major challenge, as it requires quantitative measurements of the key proteins involved. Here, we report the quantification of CTCF and cohesin, two causal regulators of topologically associating domains (TADs)...

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Detalles Bibliográficos
Publicado en:eLife
Main Authors: Cattoglio, Claudia, Pustova, Iryna, Walther, Nike, Ho, Jaclyn J, Hantsche-Grininger, Merle, Inouye, Carla J, Hossain, M Julius, Dailey, Gina M, Ellenberg, Jan, Darzacq, Xavier, Tjian, Robert, Hansen, Anders S
Formato: Artigo
Idioma:Inglês
Publicado: eLife Sciences Publications, Ltd 2019
Assuntos:
Biochemistry and Chemical Biology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6579579/
https://ncbi.nlm.nih.gov/pubmed/31205001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.40164
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