Determining cellular CTCF and cohesin abundances to constrain 3D genome models

Achieving a quantitative and predictive understanding of 3D genome architecture remains a major challenge, as it requires quantitative measurements of the key proteins involved. Here, we report the quantification of CTCF and cohesin, two causal regulators of topologically associating domains (TADs)...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:eLife
Päätekijät: Cattoglio, Claudia, Pustova, Iryna, Walther, Nike, Ho, Jaclyn J, Hantsche-Grininger, Merle, Inouye, Carla J, Hossain, M Julius, Dailey, Gina M, Ellenberg, Jan, Darzacq, Xavier, Tjian, Robert, Hansen, Anders S
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: eLife Sciences Publications, Ltd 2019
Aiheet:
Biochemistry and Chemical Biology
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6579579/
https://ncbi.nlm.nih.gov/pubmed/31205001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.40164
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