Expression of Normal and Mutant Huntingtin in the Developing Brain

Huntington’s disease (HD) is caused by a genetic mutation that results in a polyglutamine expansion in huntingtin. The time course of neuronal loss in the HD striatum and other affected brain regions before the onset of symptoms is unknown. To determine the potential influence of huntingtin on brain...

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Gepubliceerd in:J Neurosci
Hoofdauteurs: Bhide, Pradeep G., Day, Michelle, Sapp, Ellen, Schwarz, Cordula, Sheth, Ami, Kim, Johnny, Young, Anne B., Penney, John, Golden, Jeffrey, Aronin, Neil, DiFiglia, Marian
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Society for Neuroscience 1996
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6578889/
https://ncbi.nlm.nih.gov/pubmed/8757264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.16-17-05523.1996
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