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Selenium Deficiency in a Mouse Model of Sickle Cell Disease Resulted in Increased Oxygen Consumption and Aberrant Mitochondrial Retention (OR11-05-19)

OBJECTIVES: Sickle Cell Disease (SCD) is caused by a single point mutation in the β-globin gene, resulting in the polymerization of the altered hemoglobin β(S) in hypoxic conditions, affecting millions of people worldwide. Previous studies have shown that there are lower selenium levels and reduced...

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Publicat a:Curr Dev Nutr
Autors principals: Hong, Lenny, Jagadeeswaran, Ramasamy, Molokie, Robert, Lavelle, Donald, Rivers, Angela, Diamond, Alan
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6578425/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cdn/nzz044.OR11-05-19
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