Transgenic mice with increased Cu/Zn-superoxide dismutase activity are resistant to N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity

Administration of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) to mammals causes damage to the nigrostriatal dopaminergic pathway similar to that observed in Parkinson's disease. It has been suggested that the mechanism by which MPTP kills dopamine (DA) neurons involves an energy crisis...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:J Neurosci
Hlavní autoři: Przedborski, S, Kostic, V, Jackson-Lewis, V, Naini, AB, Simonetti, S, Fahn, S, Carlson, E, Epstein, CJ, Cadet, JL
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 1992
Témata:
Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6575882/
https://ncbi.nlm.nih.gov/pubmed/1578260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.12-05-01658.1992
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky