Mitochondria Targeted Peptides Protect Against 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Neurotoxicity

A large body of evidence suggests that mitochondrial dysfunction and oxidative damage play a role in the pathogenesis of Parkinson's disease (PD). A number of antioxidants have been effective in animal models of PD. We have developed a family of mitochondria-targeted peptides that can protect a...

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Bibliographic Details
Main Authors: Yang, Lichuan, Zhao, Kesheng, Calingasan, Noel Y., Luo, Guoxiong, Szeto, Hazel H., Beal, M. Flint
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc. 2009
Subjects:
Forum Original Research Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819801/
https://ncbi.nlm.nih.gov/pubmed/19203217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2009.2445
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