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NAD(+)-dependent RNA terminal 2′ and 3′ phosphomonoesterase activity of a subset of Tpt1 enzymes

The enzyme Tpt1 removes the 2′-PO(4) at the splice junction generated by fungal tRNA ligase; it does so via a two-step reaction in which (i) the internal RNA 2′-PO(4) attacks NAD(+) to form an RNA-2′-phospho-ADP-ribosyl intermediate; and (ii) transesterification of the ribose O2″ to the 2′-phosphodi...

詳細記述

保存先:
書誌詳細
出版年:RNA
主要な著者: Munir, Annum, Abdullahu, Leonora, Banerjee, Ankan, Damha, Masad J., Shuman, Stewart
フォーマット: Artigo
言語:Inglês
出版事項: Cold Spring Harbor Laboratory Press 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6573784/
https://ncbi.nlm.nih.gov/pubmed/31019096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.071142.119
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