The molecular pathogenesis of superoxide dismutase 1-linked ALS is promoted by low oxygen tension

Mutations in superoxide dismutase 1 (SOD1) cause amyotrophic lateral sclerosis (ALS). Disease pathogenesis is linked to destabilization, disorder and aggregation of the SOD1 protein. However, the non-genetic factors that promote disorder and the subsequent aggregation of SOD1 have not been studied....

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Acta Neuropathol
Main Authors: Keskin, Isil, Forsgren, Elin, Lehmann, Manuela, Andersen, Peter M., Brännström, Thomas, Lange, Dale J., Synofzik, Matthis, Nordström, Ulrika, Zetterström, Per, Marklund, Stefan L., Gilthorpe, Jonathan D.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2019
Assuntos:
Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6570705/
https://ncbi.nlm.nih.gov/pubmed/30863976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-019-01986-1
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados