Processing of DNA Double-Strand Breaks by the MRX Complex in a Chromatin Context

DNA double-strand breaks (DSBs) are highly cytotoxic lesions that must be repaired to ensure genomic stability and avoid cell death. The cellular response to DSBs is initiated by the evolutionarily conserved Mre11-Rad50-Xrs2/NBS1 (MRX/MRN) complex that has structural and catalytic functions. Further...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Front Mol Biosci
Main Authors: Casari, Erika, Rinaldi, Carlo, Marsella, Antonio, Gnugnoli, Marco, Colombo, Chiara Vittoria, Bonetti, Diego, Longhese, Maria Pia
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Molecular Biosciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6567933/
https://ncbi.nlm.nih.gov/pubmed/31231660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2019.00043
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker