The RNA binding protein Npl3 promotes resection of DNA double-strand breaks by regulating the levels of Exo1

Eukaryotic cells preserve genome integrity upon DNA damage by activating a signaling network that promotes DNA repair and controls cell cycle progression. One of the most severe DNA damage is the DNA double-strand break (DSB), whose 5΄ ends can be nucleolitically resected by multiple nucleases to cr...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Colombo, Chiara Vittoria, Trovesi, Camilla, Menin, Luca, Longhese, Maria Pia, Clerici, Michela
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2017
Fag:
Genome Integrity, Repair and Replication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5499764/
https://ncbi.nlm.nih.gov/pubmed/28472517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx347
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