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Catalytic Hydrothiolation: Regio- and Enantioselective Coupling of Thiols and Dienes

We report a Rh-catalyzed hydrothiolation of 1,3-dienes, including petroleum feedstocks. Either secondary or tertiary allylic sulfides can be generated from the selective addition of a thiol to the more substituted double bond of a diene. The catalyst tolerates a wide range of functional groups, and...

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Bibliographic Details
Published in:J Am Chem Soc
Main Authors: Yang, Xiao-Hui, Davison, Ryan T., Dong, Vy M.
Format: Artigo
Language:Inglês
Published: 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6563822/
https://ncbi.nlm.nih.gov/pubmed/30091909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b06957
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