Analysis of Whole-Exome Sequencing Data for Alzheimer Disease Stratified by APOE Genotype

IMPORTANCE: Previous genome-wide association studies of common variants identified associations for Alzheimer disease (AD) loci evident only among individuals with particular APOE alleles. OBJECTIVE: To identify APOE genotype-dependent associations with infrequent and rare variants using whole-exome...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :JAMA Neurol
Главные авторы: Ma, Yiyi, Jun, Gyungah R., Zhang, Xiaoling, Chung, Jaeyoon, Naj, Adam C., Chen, Yuning, Bellenguez, Celine, Hamilton-Nelson, Kara, Martin, Eden R., Kunkle, Brian W., Bis, Joshua C., Debette, Stéphanie, DeStefano, Anita L., Fornage, Myriam, Nicolas, Gaël, van Duijn, Cornelia, Bennett, David A., De Jager, Philip L., Mayeux, Richard, Haines, Jonathan L, Pericak-Vance, Margaret A., Seshadri, Sudha, Lambert, Jean-Charles, Schellenberg, Gerard D., Lunetta, Kathryn L., Farrer, Lindsay A.
Формат: Artigo
Язык:Inglês
Опубликовано: American Medical Association 2019
Предметы:
Original Investigation
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6563544/
https://ncbi.nlm.nih.gov/pubmed/31180460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2019.1456
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы