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CpG‐related SNPs in the MS4A region have a dose‐dependent effect on risk of late–onset Alzheimer disease

CpG‐related single nucleotide polymorphisms (CGS) have the potential to perturb DNA methylation; however, their effects on Alzheimer disease (AD) risk have not been evaluated systematically. We conducted a genome‐wide association study using a sliding‐window approach to measure the combined effects...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Aging Cell
Main Authors: Ma, Yiyi, Jun, Gyungah R., Chung, Jaeyoon, Zhang, Xiaoling, Kunkle, Brian W., Naj, Adam C., White, Charles C., Bennett, David A, De Jager, Philip L., Mayeux, Richard, Haines, Jonathan L., Pericak‐Vance, Margaret A., Schellenberg, Gerard D., Farrer, Lindsay A., Lunetta, Kathryn L.
פורמט: Artigo
שפה:Inglês
יצא לאור: John Wiley and Sons Inc. 2019
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6612647/
https://ncbi.nlm.nih.gov/pubmed/31144443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12964
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