CpG‐related SNPs in the MS4A region have a dose‐dependent effect on risk of late–onset Alzheimer disease

CpG‐related single nucleotide polymorphisms (CGS) have the potential to perturb DNA methylation; however, their effects on Alzheimer disease (AD) risk have not been evaluated systematically. We conducted a genome‐wide association study using a sliding‐window approach to measure the combined effects...

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發表在:Aging Cell
Main Authors: Ma, Yiyi, Jun, Gyungah R., Chung, Jaeyoon, Zhang, Xiaoling, Kunkle, Brian W., Naj, Adam C., White, Charles C., Bennett, David A, De Jager, Philip L., Mayeux, Richard, Haines, Jonathan L., Pericak‐Vance, Margaret A., Schellenberg, Gerard D., Farrer, Lindsay A., Lunetta, Kathryn L.
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2019
主題:
Original Papers
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6612647/
https://ncbi.nlm.nih.gov/pubmed/31144443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12964
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