CpG‐related SNPs in the MS4A region have a dose‐dependent effect on risk of late–onset Alzheimer disease

CpG‐related single nucleotide polymorphisms (CGS) have the potential to perturb DNA methylation; however, their effects on Alzheimer disease (AD) risk have not been evaluated systematically. We conducted a genome‐wide association study using a sliding‐window approach to measure the combined effects...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Ma, Yiyi, Jun, Gyungah R., Chung, Jaeyoon, Zhang, Xiaoling, Kunkle, Brian W., Naj, Adam C., White, Charles C., Bennett, David A, De Jager, Philip L., Mayeux, Richard, Haines, Jonathan L., Pericak‐Vance, Margaret A., Schellenberg, Gerard D., Farrer, Lindsay A., Lunetta, Kathryn L.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Original Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6612647/
https://ncbi.nlm.nih.gov/pubmed/31144443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12964
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