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CpG‐related SNPs in the MS4A region have a dose‐dependent effect on risk of late–onset Alzheimer disease

CpG‐related single nucleotide polymorphisms (CGS) have the potential to perturb DNA methylation; however, their effects on Alzheimer disease (AD) risk have not been evaluated systematically. We conducted a genome‐wide association study using a sliding‐window approach to measure the combined effects...

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Bibliografische gegevens
Gepubliceerd in:Aging Cell
Hoofdauteurs: Ma, Yiyi, Jun, Gyungah R., Chung, Jaeyoon, Zhang, Xiaoling, Kunkle, Brian W., Naj, Adam C., White, Charles C., Bennett, David A, De Jager, Philip L., Mayeux, Richard, Haines, Jonathan L., Pericak‐Vance, Margaret A., Schellenberg, Gerard D., Farrer, Lindsay A., Lunetta, Kathryn L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6612647/
https://ncbi.nlm.nih.gov/pubmed/31144443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12964
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