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SNPs located at CpG sites modulate genome-epigenome interaction

DNA methylation is an important molecular-level phenotype that links genotypes and complex disease traits. Previous studies have found local correlation between genetic variants and DNA methylation levels (cis-meQTLs). However, general mechanisms underlying cis-meQTLs are unclear. We conducted a cis...

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Detalhes bibliográficos
Main Authors: Zhi, Degui, Aslibekyan, Stella, Irvin, Marguerite R, Claas, Steven A, Borecki, Ingrid B, Ordovas, Jose M, Absher, Devin M, Arnett, Donna K
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3883783/
https://ncbi.nlm.nih.gov/pubmed/23811543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.25501
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