Epigenome-Wide Association Study of Fasting Measures of Glucose, Insulin, and HOMA-IR in the Genetics of Lipid Lowering Drugs and Diet Network Study

Known genetic susceptibility loci for type 2 diabetes (T2D) explain only a small proportion of heritable T2D risk. We hypothesize that DNA methylation patterns may contribute to variation in diabetes-related risk factors, and this epigenetic variation across the genome can contribute to the missing...

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Detalhes bibliográficos
Main Authors: Hidalgo, Bertha, Irvin, M. Ryan, Sha, Jin, Zhi, Degui, Aslibekyan, Stella, Absher, Devin, Tiwari, Hemant K., Kabagambe, Edmond K., Ordovas, Jose M., Arnett, Donna K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2014
Assuntos:
Genetics/Genomes/Proteomics/Metabolomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3968438/
https://ncbi.nlm.nih.gov/pubmed/24170695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db13-1100
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