α-GalCer and iNKT Cell-Based Cancer Immunotherapy: Realizing the Therapeutic Potentials

NKT cells are CD1d-restricted innate-like T cells expressing both T cell receptor and NK cell markers. The major group of NKT cells in both human and mice is the invariant NKT (iNKT) cells and the best-known function of iNKT cells is their potent anti-tumor function in mice. Since its discovery 25 y...

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Vydáno v:Front Immunol
Hlavní autoři: Zhang, Yingting, Springfield, Ryan, Chen, Siyang, Li, Xin, Feng, Xiaotian, Moshirian, Rosa, Yang, Rirong, Yuan, Weiming
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6562299/
https://ncbi.nlm.nih.gov/pubmed/31244823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01126
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