Expression of CD1c enhances human invariant NKT cell activation by α-GalCer

Invariant natural killer T (iNKT) cells are innate T lymphocytes that specifically recognize α-linked glycosphingolipids (α-GSLs) as antigens presented by CD1d molecules. Activating iNKT cells by administering α-GSLs improves disease outcomes in murine cancer models and, thus, there is great interes...

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Main Authors: Fox, Lisa M., Miksanek, Jennifer, May, Nathan A., Scharf, Louise, Lockridge, Jennifer L., Veerapen, Natacha, Besra, Gurdyal S., Adams, Erin J., Hudson, Amy W., Gumperz, Jenny E.
格式: Artigo
語言:Inglês
出版: Academy of Cancer Immunology 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3721260/
https://ncbi.nlm.nih.gov/pubmed/23885215
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