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α-S-GalCer: Synthesis and Evaluation for iNKT Cell Stimulation

The synthesis and evaluation for iNKT stimulation of α-S-galactosylceramide is reported. Prepared by alkylation of a galactosylthiol, this analog of the potent immunostimulatory agent, KRN7000, did not stimulate iNKT cells either in vitro or in vivo.

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Bibliographische Detailangaben
Hauptverfasser: Blauvelt, Marisa L., Khalili, Maryam, Jaung, Weonjoo, Paulsen, Janet, Anderson, Amy C., Wilson, S. Brian, Howell, Amy R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2628538/
https://ncbi.nlm.nih.gov/pubmed/18993065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2008.10.086
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