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α-S-GalCer: Synthesis and Evaluation for iNKT Cell Stimulation
The synthesis and evaluation for iNKT stimulation of α-S-galactosylceramide is reported. Prepared by alkylation of a galactosylthiol, this analog of the potent immunostimulatory agent, KRN7000, did not stimulate iNKT cells either in vitro or in vivo.
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2628538/ https://ncbi.nlm.nih.gov/pubmed/18993065 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2008.10.086 |
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