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Structure of the gene therapy vector, adeno-associated virus with its cell receptor, AAVR

Adeno-associated virus (AAV) vectors are preeminent in emerging clinical gene therapies. Generalizing beyond the most tractable genetic diseases will require modulation of cell specificity and immune neutralization. Interactions of AAV with its cellular receptor, AAVR, are key to understanding cell-...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:eLife
Egile Nagusiak: Meyer, Nancy L, Hu, Guiqing, Davulcu, Omar, Xie, Qing, Noble, Alex J, Yoshioka, Craig, Gingerich, Drew S, Trzynka, Andrew, David, Larry, Stagg, Scott M, Chapman, Michael Stewart
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: eLife Sciences Publications, Ltd 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6561701/
https://ncbi.nlm.nih.gov/pubmed/31115336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.44707
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