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Structure of the gene therapy vector, adeno-associated virus with its cell receptor, AAVR

Adeno-associated virus (AAV) vectors are preeminent in emerging clinical gene therapies. Generalizing beyond the most tractable genetic diseases will require modulation of cell specificity and immune neutralization. Interactions of AAV with its cellular receptor, AAVR, are key to understanding cell-...

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Pubblicato in:eLife
Autori principali: Meyer, Nancy L, Hu, Guiqing, Davulcu, Omar, Xie, Qing, Noble, Alex J, Yoshioka, Craig, Gingerich, Drew S, Trzynka, Andrew, David, Larry, Stagg, Scott M, Chapman, Michael Stewart
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6561701/
https://ncbi.nlm.nih.gov/pubmed/31115336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.44707
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