Divergent engagements between adeno-associated viruses with their cellular receptor AAVR

Adeno-associated virus (AAV) receptor (AAVR) is an essential receptor for the entry of multiple AAV serotypes with divergent rules; however, the mechanism remains unclear. Here, we determine the structures of the AAV1-AAVR and AAV5-AAVR complexes, revealing the molecular details by which PKD1 recogn...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Zhang, Ran, Xu, Guangxue, Cao, Lin, Sun, Zixian, He, Yong, Cui, Mengtian, Sun, Yuna, Li, Shentao, Li, Huapeng, Qin, Lan, Hu, Mingxu, Yuan, Zhengjia, Rao, Zipei, Ding, Wei, Rao, Zihe, Lou, Zhiyong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6704107/
https://ncbi.nlm.nih.gov/pubmed/31434885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11668-x
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