Structure of the gene therapy vector, adeno-associated virus with its cell receptor, AAVR

Adeno-associated virus (AAV) vectors are preeminent in emerging clinical gene therapies. Generalizing beyond the most tractable genetic diseases will require modulation of cell specificity and immune neutralization. Interactions of AAV with its cellular receptor, AAVR, are key to understanding cell-...

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Veröffentlicht in:eLife
Hauptverfasser: Meyer, Nancy L, Hu, Guiqing, Davulcu, Omar, Xie, Qing, Noble, Alex J, Yoshioka, Craig, Gingerich, Drew S, Trzynka, Andrew, David, Larry, Stagg, Scott M, Chapman, Michael Stewart
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications, Ltd 2019
Schlagworte:
Microbiology and Infectious Disease
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6561701/
https://ncbi.nlm.nih.gov/pubmed/31115336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.44707
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