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Structure of the gene therapy vector, adeno-associated virus with its cell receptor, AAVR

Adeno-associated virus (AAV) vectors are preeminent in emerging clinical gene therapies. Generalizing beyond the most tractable genetic diseases will require modulation of cell specificity and immune neutralization. Interactions of AAV with its cellular receptor, AAVR, are key to understanding cell-...

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Библиографические подробности
Опубликовано в: :eLife
Главные авторы: Meyer, Nancy L, Hu, Guiqing, Davulcu, Omar, Xie, Qing, Noble, Alex J, Yoshioka, Craig, Gingerich, Drew S, Trzynka, Andrew, David, Larry, Stagg, Scott M, Chapman, Michael Stewart
Формат: Artigo
Язык:Inglês
Опубликовано: eLife Sciences Publications, Ltd 2019
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6561701/
https://ncbi.nlm.nih.gov/pubmed/31115336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.44707
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