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Consensus sequence design as a general strategy to create hyperstable, biologically active proteins
Consensus sequence design offers a promising strategy for designing proteins of high stability while retaining biological activity since it draws upon an evolutionary history in which residues important for both stability and function are likely to be conserved. Although there have been several repo...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6561275/ https://ncbi.nlm.nih.gov/pubmed/31110018 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1816707116 |
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