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Consensus sequence design as a general strategy to create hyperstable, biologically active proteins

Consensus sequence design offers a promising strategy for designing proteins of high stability while retaining biological activity since it draws upon an evolutionary history in which residues important for both stability and function are likely to be conserved. Although there have been several repo...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Sternke, Matt, Tripp, Katherine W., Barrick, Doug
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6561275/
https://ncbi.nlm.nih.gov/pubmed/31110018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1816707116
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