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Consensus sequence design as a general strategy to create hyperstable, biologically active proteins

Consensus sequence design offers a promising strategy for designing proteins of high stability while retaining biological activity since it draws upon an evolutionary history in which residues important for both stability and function are likely to be conserved. Although there have been several repo...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Sternke, Matt, Tripp, Katherine W., Barrick, Doug
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6561275/
https://ncbi.nlm.nih.gov/pubmed/31110018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1816707116
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