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The use of consensus sequence information to engineer stability and activity in proteins

The goal of protein design is to create proteins that are stable, soluble, and active. Here we focus on one approach to protein design in which sequence information is used to create a “consensus” sequence. Such consensus sequences comprise the most common residue at each position in a multiple sequ...

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Bibliografiske detaljer
Udgivet i:Methods Enzymol
Main Authors: Sternke, Matt, Tripp, Katherine W., Barrick, Doug
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8098710/
https://ncbi.nlm.nih.gov/pubmed/32896279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2020.06.001
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