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Enhancing the stability and folding rate of a repeat protein through the addition of consensus repeats

Repeat proteins are constructed from a linear array of modular units, giving rise to an overall topology lacking long-range interactions. This suggests that stabilizing repeat modules based on consensus information might be added to a repeat protein domain, allowing it to be extended without alterin...

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Bibliografiske detaljer
Main Authors: Tripp, Katherine W., Barrick, Doug
Format: Artigo
Sprog:Inglês
Udgivet: 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1851695/
https://ncbi.nlm.nih.gov/pubmed/17067634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2006.09.092
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