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Predicting repeat protein folding kinetics from an experimentally determined folding energy landscape

The Notch ankyrin domain is a repeat protein whose folding has been characterized through equilibrium and kinetic measurements. In previous work, equilibrium folding free energies of truncated constructs were used to generate an experimentally determined folding energy landscape (Mello and Barrick,...

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Autores principales: Street, Timothy O, Barrick, Doug
Formato: Artigo
Lenguaje:Inglês
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708030/
https://ncbi.nlm.nih.gov/pubmed/19177351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.9
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