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Predicting coupling limits from an experimentally determined energy landscape

Repeat proteins are composed of tandem structural modules in which close contacts do not extend beyond adjacent repeats. Despite the local nature of these close contacts, repeat proteins often unfold as a single, highly coupled unit. Previous studies on the Notch ankyrin domain suggest that this lac...

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Autors principals: Street, Timothy O., Bradley, Christina M., Barrick, Doug
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1829238/
https://ncbi.nlm.nih.gov/pubmed/17360387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0608756104
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