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Predictive energy landscapes for protein–protein association

We investigate protein–protein association using the associative-memory, water-mediated, structure, and energy model (AWSEM), a coarse-grained protein folding model that has been optimized using energy-landscape theory. The potential was originally parameterized by enforcing a funneled nature for a...

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Hlavní autoři: Zheng, Weihua, Schafer, Nicholas P., Davtyan, Aram, Papoian, Garegin A., Wolynes, Peter G.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511104/
https://ncbi.nlm.nih.gov/pubmed/23129648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1216215109
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