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Braiding topology and the energy landscape of chromosome organization proteins

Assemblies of structural maintenance of chromosomes (SMC) proteins and kleisin subunits are essential to chromosome organization and segregation across all kingdoms of life. While structural data exist for parts of the SMC−kleisin complexes, complete structures of the entire complexes have yet to be...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Krepel, Dana, Davtyan, Aram, Schafer, Nicholas P., Wolynes, Peter G., Onuchic, José N.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6983425/
https://ncbi.nlm.nih.gov/pubmed/31888987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1917750117
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