Red blood cells modulate structure and dynamics of venous clot formation in sickle cell disease

Sickle cell disease (SCD) is associated with chronic activation of coagulation and an increased risk of venous thromboembolism. Erythrocyte sickling, the primary pathologic event in SCD, results in dramatic morphological changes in red blood cells (RBCs) because of polymerization of the abnormal hem...

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Dettagli Bibliografici
Pubblicato in:Blood
Autori principali: Faes, Camille, Ilich, Anton, Sotiaux, Amandine, Sparkenbaugh, Erica M., Henderson, Michael W., Buczek, Laura, Beckman, Joan D., Ellsworth, Patrick, Noubouossie, Denis F., Bhoopat, Lantarima, Piegore, Mark, Renoux, Céline, Bergmeier, Wolfgang, Park, Yara, Ataga, Kenneth I., Cooley, Brian, Wolberg, Alisa S., Key, Nigel S., Pawlinski, Rafal
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2019
Soggetti:
Thrombosis and Hemostasis
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6557624/
https://ncbi.nlm.nih.gov/pubmed/30952675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2019000424
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