Abnormal plasma clot formation and fibrinolysis reveal bleeding tendency in patients with partial factor XI deficiency

Individuals with factor XI (FXI) deficiency have a variable bleeding risk that cannot be predicted from plasma FXI antigen or activity. This limitation can result in under- or overtreatment of patients and risk of bleeding or thrombosis. Previously, plasma clot fibrinolysis assays showed sensitivity...

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Bibliographische Detailangaben
Veröffentlicht in:Blood Adv
Hauptverfasser: Gidley, Gillian N., Holle, Lori A., Burthem, John, Bolton-Maggs, Paula H. B., Lin, Feng-Chang, Wolberg, Alisa S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2018
Schlagworte:
Thrombosis and Hemostasis
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5965046/
https://ncbi.nlm.nih.gov/pubmed/29760205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017015123
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