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Factor XIII in plasma, but not in platelets, mediates red blood cell retention in clots and venous thrombus size in mice
The transglutaminase factor XIII (FXIII) stabilizes clots against mechanical and biochemical disruption and is essential for hemostasis. In vitro and in vivo models of venous thrombosis demonstrate that FXIII mediates clot size by promoting red blood cell (RBC) retention. However, the key source of...
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| Udgivet i: | Blood Adv |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society of Hematology
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5761627/ https://ncbi.nlm.nih.gov/pubmed/29344582 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017011890 |
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