Factor XIII activity mediates red blood cell retention in venous thrombi

Venous thrombi, fibrin- and rbc-rich clots triggered by inflammation and blood stasis, underlie devastating, and sometimes fatal, occlusive events. During intravascular fibrin deposition, rbc are thought to become passively trapped in thrombi and therefore have not been considered a modifiable throm...

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Detalhes bibliográficos
Main Authors: Aleman, Maria M., Byrnes, James R., Wang, Jian-Guo, Tran, Reginald, Lam, Wilbur A., Di Paola, Jorge, Mackman, Nigel, Degen, Jay L., Flick, Matthew J., Wolberg, Alisa S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4109540/
https://ncbi.nlm.nih.gov/pubmed/24983320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI75386
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