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Abnormal plasma clot structure and stability distinguish bleeding risk in patients with severe factor XI deficiency

BACKGROUND: Factor XI (FXI) deficiency is a rare autosomal recessive disorder. Many patients with even very low FXI levels (<20 IU/dL) are asymptomatic or exhibit only mild bleeding, whereas others experience severe bleeding usually following trauma. Neither FXI antigen nor activity predicts blee...

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Main Authors: Zucker, Michal, Seligsohn, Uri, Salomon, Ophira, Wolberg, Alisa S.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4107079/
https://ncbi.nlm.nih.gov/pubmed/24815347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.12600
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