EGLN2 DNA methylation and expression interact with HIF1A to affect survival of early-stage NSCLC

Hypoxia occurs frequently in human cancers and promotes stabilization and activation of hypoxia inducible factor (HIF). HIF-1α is specific for the hypoxia response, and its degradation mediated by three enzymes EGLN1, EGLN2 and EGLN3. Although EGLNs expression has been found to be related to prognos...

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Publicat a:Epigenetics
Autors principals: Zhang, Ruyang, Lai, Linjing, He, Jieyu, Chen, Chao, You, Dongfang, Duan, Weiwei, Dong, Xuesi, Zhu, Ying, Lin, Lijuan, Shen, Sipeng, Guo, Yichen, Su, Li, Shafer, Andrea, Moran, Sebastian, Fleischer, Thomas, Bjaanæs, Maria Moksnes, Karlsson, Anna, Planck, Maria, Staaf, Johan, Helland, Åslaug, Esteller, Manel, Wei, Yongyue, Chen, Feng, Christiani, David C.
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2019
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6557590/
https://ncbi.nlm.nih.gov/pubmed/30665327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2019.1573066
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