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EGLN2 DNA methylation and expression interact with HIF1A to affect survival of early-stage NSCLC
Hypoxia occurs frequently in human cancers and promotes stabilization and activation of hypoxia inducible factor (HIF). HIF-1α is specific for the hypoxia response, and its degradation mediated by three enzymes EGLN1, EGLN2 and EGLN3. Although EGLNs expression has been found to be related to prognos...
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| Wydane w: | Epigenetics |
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| Główni autorzy: | , , , , , , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Taylor & Francis
2019
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6557590/ https://ncbi.nlm.nih.gov/pubmed/30665327 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2019.1573066 |
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