Epigenetic modifications in KDM lysine demethylases associate with survival of early-stage NSCLC

BACKGROUND: KDM lysine demethylase family members are related to lung cancer clinical outcomes and are potential biomarkers for chemotherapeutics. However, little is known about epigenetic alterations in KDM genes and their roles in lung cancer survival. METHODS: Tumor tissue samples of 1230 early-s...

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Publicado en:Clin Epigenetics
Autores principales: Wei, Yongyue, Liang, Junya, Zhang, Ruyang, Guo, Yichen, Shen, Sipeng, Su, Li, Lin, Xihong, Moran, Sebastian, Helland, Åslaug, Bjaanæs, Maria M., Karlsson, Anna, Planck, Maria, Esteller, Manel, Fleischer, Thomas, Staaf, Johan, Zhao, Yang, Chen, Feng, Christiani, David C.
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5879927/
https://ncbi.nlm.nih.gov/pubmed/29619118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-018-0474-3
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